Synthesis and characterization of zinc complexes of cefpodoxime, Amoxicillin and montelukast
Loading...
Date
2016
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
University of Management and Technolog
Abstract
Three different complexes of zinc with medicinally important drugs are synthesized and characterized by using FT-IR and thermogravimetric analyses. Furthermore, a co-ligand, 8-hydoxyquinoline is also attached to fill the vacant spaces of d-orbitals of zinc metal. Zinc complexes of drugs are confirmed by shifting of carboxylate (COO-) stretching vibration while the coordination of zinc with 8-hydroxyquinoline is confirmed by the Zn-N stretching vibration. TGA results of complexes further confirm the high stability of complexes.
Description
supervised by:Dr. Khurram Shahzad Munawar
Keywords
Synthesized and characterized, Carboxylate (COO-), MS thesis