Synthesis, characterization and biological activities of aurones

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dc.contributor.authorRasheed, Rukhsana
dc.date.accessioned2018-04-13T06:07:52Z
dc.date.available2018-04-13T06:07:52Z
dc.date.issued2017
dc.descriptionSupervised by: Dr. Sohail Nadeemen_US
dc.description.abstractMedicinal plants are the back bone in the treatment of various diseases. Flavonoids has been used for many ailments. Aurones belongs to the family of flavonoids, these are naturally occurring in many plants which play important role to give bright yellow color to the petals of different flowers. Due to the presence of double bond aurones have two types of configurations (Z/E). Aurones are useful in anti-fungal, anti-viral, anti-diabetic and anti-cancer activities. The present data was undertaken to find out the antibacterial activity and evaluation of various compounds which present in non-polar profile. The inhibition zone diameters against four tested bacteria are studied in antibacterial activity. Aurones were prepared by adding suitable quantities of benzaldehyde sample (such as p-anisole, 2,4-dimethoxy benzaldehyde and 2-hydroxy acetophenone). All these samples were fully characterized through IR. Results of antibacterial activity of methanolic extract showed that auronesposses less resistance against the pathogenic bacteria. This study was also show that methanolic extract of aurones was less potent against the Gran-positive than the Gram-negative bacteria. This study will be very useful to indicate the biosynthetic and pharmacological activity of plants for drug discovery.en_US
dc.identifier.urihttps://escholar.umt.edu.pk/handle/123456789/2993
dc.language.isoenen_US
dc.publisherUniversity of Management and Technologen_US
dc.subjectconfigurations (Z/E). Auronesen_US
dc.subjectquantities of benzaldehyde sampleen_US
dc.subjectMS thesisen_US
dc.titleSynthesis, characterization and biological activities of auronesen_US
dc.typeThesisen_US
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