INCIDENCE AND ANTIBIOTIC SUSCEPTIBILITY PATTERN OF PROTEUS SPECIES IN DIFFERENT CLINICAL SOURCES/SPECIMENS
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Date
2016
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Publisher
University of Management and Technology Lahore
Abstract
Proteus is one of the specie offamily of Enterobacteriaceae which is cause of most of the community infection. There are various reasons for different diseases. They may be spread from contact with the effected persons. This type of infection is dangerous one. The occurance of infection of Proteus is due to the resistance and susceptible pattern with different types of infection.
Methodology: Different types of samples were collected from various patients including sites of infections like urine, wound, tissues, puss, blood, cerebrospinal fluid, upper respiratory tract infection(URTI), vaginal tract infection(VTI), upper transparatory infection(UTI). The sample were collected in culture of blood bottle. All the sample were collected for culture in laboratory through MacConkey ager and blood ager plates at 37 C for 1 day. The resistance and susceptibility pattern of proteous specie was determine using different sites of infection. Different antibiotics were compare on the each site of infection.
Results: This study of proteous specie include total samples of 955 patients and out of these 173 (18.12%) were positive for proteous specie. Forty two antibiotics were used against susceptibility pattern for proteous specie. The most samples were Puss 152 (87.86 %) sample. The wound samples were 12( 6.94% ), tissue sample was only 1 (0.58%), blood samples were 2 (1.76%), Csf was only 1 (0.58%), urinary tract infection was only 1 (0.58%), and no sample was found in upper respiratory tract infection and vaginal tract infection. In our study Azythromycin and Norfloxacin were showed 100% resistant and Amoxicillin was showed 64.40% sensitivity antibiotic for the treatment of Proteous specie in different sites of infection.
Conclusion: It is clear from above data that efficiency of each antibiotic was different for different sites of infections. Doctors should recommended that before giving antibiotics should aware susceptibility of each patient, because susceptibility is different from patient to patient. This type of study demands that at national level, before recommendation should confirm susceptibility and resistant pattern.
Description
Supervised By:Dr. Muhammad Sohail Afzal
Keywords
Proteus, Community infection, M.Phil Thesis