Antibacterial activity of cuprous oxide nanoparticles
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Date
2017
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Publisher
University of Management and Technology Lahore
Abstract
Cuprous oxide nanoparticles were prepared by using copper sulfate pentahydrate and small amount of hydrazine as reducing agent. The antibacterial activity of cuprous oxide nanoparticles was evaluated against different bacteria's such as Pseudomonas, Streptococcus mutans, Staphylococcus areus, Klebsiella pneumonia andEschericia coli. For this purpose petri dishes were prepared containing inoculums and bacteria from slant was injected, amoxicillin was used as a standard antibiotic drug along with water as solvent. Amoxicillin is a famous antiseptic drug. Dilutions of cuprous oxide nanoparticles were prepared of 1%, 0.5%, 0.25% and 0.125% respectively. Properties of nanoparticles were studied by using XRD pattern. Cuprous oxide nanoparticles showed antimicrobial efficiency against all of the bacteria byagar well diffusion method. Results showed that cuprous oxide nanoparticles could restrain the growth of Pseudomonas, E.coli, St.aureus, K.pneumonia and St.mutans. Highest efficiency was achieved against Klebsiella pneumonia for 1% concentration and lowest efficiency was achieved against Streptococcus mutans and Pseudomonas for 0.125% concentration. Therefore, it can be concluded that cuprous oxide nanoparticles show efficient antimicrobial properties and could be replaced in antibiotic drugs as antimicrobial agent.
Description
Supervised by:Humaira Khan
Keywords
Pseudomonas, Amoxicillin, BS Thesis