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Browsing School of Science (SSC) by Subject "4-isopropylbenzaldehyde"

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    Transition metal complexes of a bidentate schiff base derived by condensation of 2-aminothiophenol and 4-isopropylbenzaldehyde
    (University of Management and Technology, 2017) Kanwal, Hira
    A condensation reaction between 2-aminothiophenol and 4-isopropylbenzaldehyde is carring out for the formation of 2(4-isoprppylphenyl) benzo[d]thiazole Schiff base. The molar ratio of the reaction is 1:1. Different characterization techniques are used for synthesized compounds. The prepared compounds are characterized by FT-IR, UV-Visible spectroscopy and conductance measurement. The stretching vibration of FT-IR data proved that azomethine (CH=N) is found in the ligand at 1620cm-1. The shifting of band to lower wave number at 1605-1636cm-1 in the complex which confirms the presence of azomethine group (-N=CH) and coordination with metal (M-N). UV-Visible spectral studies revealed that π-π* transitions were found in all compounds. The molar conductivity values indicate that all compounds are non-electrolytes. The XRD Data revealed that crystal structure of the ligand is triclinic and have P-1 space. Biological studies have shown that metal complexes inhibit ALP activity by attaching at the active sites of enzymes. The compounds also tested for in vitro antimicrobial screening by well diffusion method. A result indicates that metal complexes are good antimicrobial agents than ligand. The Vanadyl complex helpful in normalizing the blood glucose level and also suppress lipolysis. Vanadyl complex also play an important role in lowering the cholesterol level in blood.