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EVALUATION OF ANTI-DIABETIC ACTIVITY OF ESSENTIL OIL OF ARTEMISIA MARITIMA. L IN HYPERGLYCEMIC RATS
(UMT, Lahore, 2025) Iqra Habib
This study investigated into the toxicity and antidiabetic properties of an essential oil that was extracted from Artemisia maritima. Notably, this research represents the first investigation into the antidiabetic effect of Artemisia maritima essential oil. The steam distillation process was used to extract the essential oil. The essential oil was analyzed by gas romatography (GC), GC/mass spectrometry (GC/MS). There were twelve compounds found in Artemisia maritima. The primary constituents of oil from Artemisia maritima were Eucalyptol, (+)-2-Bornanone, 3-cyclohexen-1-ol, 4-methyl-1-(1-methylethyl)-, (R)-, (+)-4-Carene, o-Cymene, gamma- Terpinene, Thujone, 4-Isopropyl-1methlycyclohex-2-enol, alpha-Terpineol, 2-Cyclohexen-1- one,3-methyi-6-(1-methylethyl)-, Bicyclo[7.2.0]undee-4-ene,4,11,11-trimethy-8-methylene- and Germacrene D. The exhibited biological potential of Artemisia maritima may be attributed to the active ingredients identified by the phytochemical analysis. Rats with diabetes caused by streptozotocin were given essential oil of Artemisia maritima for a period of 28 days. The rats were killed after 28 days, and heart punctures were used to obtain blood samples. Blood glucose levels as well as liver and kidney enzyme levels were assessed. These results suggest that diabetes mellitus can be managed using the AMEO.