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Role of mercury toxicity in kidney disease incidence in Pakistan
(University of Management and Technology Lahore, 2016) Abubakar, Muhammad
High level of mercury can cause severe effects on kidneys including mental disorder. If its level exceeded from 50 µg/dL then it can be very harmful for people. Goal of the present study is to evaluate serum uric acid as biomarker like blood urea and serum creatinine biomarkers of kidney disorder and to check the co-relation of abnormal level of mercury with serum creatinine, serum urea and serum uric acid. Methods: Hundred subjects were randomly enlisted in this study, having kidney disorders, for example, renal disorder, and co-relation of mercury with biomarkers was analyzed by Atomic Absorption Spectroscopy (AAS). Results: Serum uric acid level was raised in 55 patients while blood urea and serum creatinine level was found in 72 and 83 patients individually. High serum uric acid concentration was observed in 70.73% females (p=0.0003) and 44.07% males (p=0.2692). The co-relation between mercury (Hg), serum creatinine, serum urea and serum uric acid was found insignificant. Conclusion: co-relation between mercury (Hg), serum creatinine, serum urea and serum uric acid level was insignificant. Serum uric acid is raised up to high level in patients with impeded renal function in all members. Higher levels of serum uric acid were not essentially associated with serum creatinine and blood urea level in all patients.