Ginseng phytochemicals as therapeutics in oncology: Recent perspectives

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dc.contributor.authorMajeed, Fatima
dc.contributor.authorZahur Malik, Fozia
dc.contributor.authorAhmed, Zaheer
dc.contributor.authorAfreen, Asma
dc.contributor.authorAfzal, Muhammad Naveed
dc.contributor.authorKhalid, Nauman
dc.date.accessioned2019-03-19T11:32:52Z
dc.date.available2019-03-19T11:32:52Z
dc.date.issued2018
dc.description.abstractDuring the last few decades, cancer has mushroomed as a major health issue; and almost all drugs used for its therapy are very toxic with lethal side effects. Complementary and alternative medicines gain popularity among health professionals in recent era owing to its preventive mechanism against side effect chemotherapeutic drugs. Efforts are focused by scientists to isolate compounds from medicinal plant that have chemotherapeutic attributes; and ability to neutralize the side effects of chemotherapy. Ginseng is an oriental medicinal recipe from Araliceae family and Panax species. The chemotherapeutic effect of ginsenoside is resultant of its appetites, antiproliferative, anti-angiogenic, anti-inflammatory and anti-oxidant properties. The anticancer effect of ginseng is proven in various types of cancer, including; breast, lung, liver, colon and skin cancer. It increases the mitochondrial accumulation of apoptosis protein and downregulate the expression of anti-apoptotic protein. It also aids in the reduction of alopecia, fatigue and nausea, the known side effects of chemotherapeutic drugs. The aim of the present review is to provide the brief review of the recent researches related to mechanism of action of ginseng in different types of cancer as complementary and alternative medicine on different body organs.en_US
dc.identifier.citationMajeed, F., Malik, F. Z., Ahmed, Z., Afreen, A., Afzal, M. N., & Khalid, N. (2018). Ginseng phytochemicals as therapeutics in oncology: Recent perspectives. Biomedicine & Pharmacotherapy, 100, 52-63. doi: 10.1016/j.biopha.2018.01.155. (Mohammad Naveed Afzal (SHS), Nauman Khalid, (JCR Listed))en_US
dc.identifier.urihttps://escholar.umt.edu.pk/handle/123456789/3695
dc.language.isoenen_US
dc.publisherBiomedicine & Pharmacotherapyen_US
dc.subjectGinseng Phytochemicals Chemotherapy Colon Liver Lung Skin canceren_US
dc.titleGinseng phytochemicals as therapeutics in oncology: Recent perspectivesen_US
dc.typeArticleen_US
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