Bacteriophages: an overview of the control strategies against multiple bacterial infections in different fields

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dc.contributor.authorMohsin Jamal
dc.contributor.authorSayed M. A. U. S. Bukhari
dc.contributor.authorSaadia Andleeb
dc.contributor.authorMuhammad Ali
dc.contributor.authorSana Raza
dc.contributor.authorMuhammad A. Nawaz
dc.contributor.authorTahir Hussain
dc.contributor.authorSadeeq u. Rahman
dc.contributor.authorSyed S. A. Shah
dc.date.accessioned2019-07-09T11:32:14Z
dc.date.available2019-07-09T11:32:14Z
dc.date.issued2018
dc.description.abstractBacteriophages (phages/viruses) need host bacteria to replicate and propagate. Primarily,abacteriophagecontainsahead/capsidtoencapsidatethegeneticmaterial. Somephagescontaintails.Phagesencodeendolysinstohydrolyzebacterialcellwall. The two main classes of phages are lytic or virulent and lysogenic or temperate. In comparison with antibiotics, to deal with bacterial infections, phage therapy is thought to be more effective. In 1921, the use of phages against bacterial infections was first demonstrated. Later on, in humans, phage therapy was used to treat skin infections caused by Pseudomonas species. Furthermore, phages were successfully employed against infections in animals – calves, lambs, and pigs infected with Escherichiacoli.Inagriculture,forinstance,phageshavesuccessfullybeenusede.g., Appleblossominfection,causedbyErwiniaamylovora,waseffectivelycateredwith the use of bacteriophages. Bacteriophages were also used to control E. coli, Salmonella, Listeria, and Campylobacter contamination in food. Comparatively, phage display is a recently discovered technology, whereby, bacteriophages play a significant role. This review is an effort to collect almost recent and relevant information regarding applications and complications associated with the use of bacteriophages.en_US
dc.identifier.citationJamal, M., Bukhari, S. M., Andleeb, S., Ali, M., Raza, S., Nawaz, M. A., ... & Shah, S. S. (2019). Bacteriophages: an overview of the control strategies against multiple bacterial infections in different fields. Journal of basic microbiology, 59(2), 123-133.en_US
dc.identifier.urihttps://escholar.umt.edu.pk/handle/123456789/3750
dc.language.isoenen_US
dc.publisherJournal of basic microbiologyen_US
dc.subjectbacteriophage, endolysins, lysogenic, lytic, phage therapyen_US
dc.titleBacteriophages: an overview of the control strategies against multiple bacterial infections in different fieldsen_US
dc.typeArticleen_US
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