Antidiabetic and antioxidant activity of Triticum aestivum sprout and hedera helix l.
| dc.contributor.author | FAIZA KHALID | |
| dc.date.accessioned | 2025-12-02T22:17:25Z | |
| dc.date.available | 2025-12-02T22:17:25Z | |
| dc.date.issued | 2018 | |
| dc.description.abstract | Medicinal plants are in use since old times for the treatment of human diseases, because of their reliable and powerful chemical composition. Triticum aestivum (wheat sprout) and Hedera helix L (ivy) are an oldest therapeutic plants. The aim of current work was to evaluate in vivo antidiabetic and antioxidant activities, using Triticum aestivum sprout and Hedera helix. L. To evaluate antidiabetic potential, acarbose was used as standard and was checked against alpha amylase enzyme. Using different concentrations of (extract of Triticum aestivum sprout and Hedera helix. L), inhibition percentage are observed. For methanolic extracts, the inhibition ranges of Triticum aestivum sprout was 26.05% to 77.41% and Hedera helix. L ranges from 34.29% to 82.45%. These inhibitions were closely associated with that of acarbose inhibition percentages ranged from 38.20% to 86.20%. In case of antioxidant activity, BHT was used as positive control. Using different concentrations of Triticum aestivum sprout and Hedera helix. L inhibition percentage was observed. For methanolic extracts, the inhibition ranges of Triticum aestivum sprout was 20.20% to 70.31% and Hedera helix. L ranges from 38.55% to 84.84%. These inhibitions were closely related with that of BHT ranges inhibition percentages ranged from 50.11% to 90.32%.Results showed that these methanolic extracts revealed significant α-amylase inhibition action with an IC50 value of 0.027 and 0.023 Triticum aestivum sprout and Hedera helix. L respectively as associated with acarbose (IC 50 value 0.0197). Whereas in antioxidant the IC50 value of Triticum aestivum sprout and Hedera helix. L is 0.0321 and 0.0223 respectively with standard (BHT) having IC 50 value 0.0197. It is concluded that extract of Triticum aestivum sprout and Hedera helix. L concentrations were active against both activities and this potential increased as the concentration of extracts increased. However, percentages of inhibition were less than standard drugs. | |
| dc.identifier.uri | https://escholar.umt.edu.pk/handle/123456789/14705 | |
| dc.language.iso | en | |
| dc.publisher | UMT, Lhr | |
| dc.title | Antidiabetic and antioxidant activity of Triticum aestivum sprout and hedera helix l. | |
| dc.type | Thesis |
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