Vanadium-catalyzed esterification of carboxylates: synthesis, x-ray crystal structure and biological studies.

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dc.contributor.authorKhurram Shahzad Munawar
dc.date.accessioned2018-11-24T11:07:12Z
dc.date.available2018-11-24T11:07:12Z
dc.date.issued2016
dc.description.abstractThe potentials of vanadium (III) chloride as catalyst were checked for the esterification of substituted carboxylic acids with methanol. The synthesised precursors and methyl esters formed were characterised by various analytical techniques such as FT-IR, 1H-NMR, 13C-NMR and single crystal analysis. The antimicrobial activities of the carboxylates and their methyl esters were found good against various strains of bacteria (Escherichia coli, Bacillus subtilis, Staphylococcus aureus and Pasteurella multocida) and fungi (Alternaria alternata, Ganoderma lucidum and Penicillium notatum). All these esters were tested for their activity against the alkaline phosphatase (ALP) and Methyl 4-oxo-4-(2,4,6-trichlorophenylamino)but- 2-enoate (compound 1) was found to be potent inhibitor while Methyl 4-(3,4-dichlorophenylamino)-4-oxobut-2-enoate (compound 2) showed intercalative mode of binding with DNA.en_US
dc.identifier.citationMunawar, K. S., Ali, S., Khalid, N., Tahir M. N., & Abbas, S. M. (2016). Vanadium-Catalyzed Esterification of Carboxylates: Synthesis, X-Ray Crystal Structure and Biological Studies. Chemistry Journal, 6(1), 1-9. (Khurram Shahzad Munawar (Chemistry/SSC), (NOT RECOGNIZED BY HEC))en_US
dc.identifier.issn2049-954X
dc.identifier.urihttps://escholar.umt.edu.pk/handle/123456789/3446
dc.publisherChemistry Journal, Scientific Journalen_US
dc.subjectChemistryen_US
dc.subjectVanadium, Coordination Modes, Vibrational Spectroscopy, Antimicrobial Activities, Bacteria, Fungien_US
dc.titleVanadium-catalyzed esterification of carboxylates: synthesis, x-ray crystal structure and biological studies.en_US
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