Natural Products: Bioactivity, Biochemistry, and Biological Effects in Cancer and Disease Therapy
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Date
2013
Journal Title
Journal ISSN
Volume Title
Publisher
Hindawi Publishing Corporation
Abstract
The drug discovery for chemoprevention and chemotherapy
remains a challenge. Natural products-derived extracts and
compounds are frequently reported to discover therapeutic
agents for disease and cancer.
The overall scenario of this special issue ofThe Scientific
World Journal presents the recent advances in biological
function of selected natural products for cancer and disease
therapy in terms of crude extracts and components. Some
studies describe the bioinformatics tool to help to investigate
the field of natural products.The papers by S. Guleria et al. and C.-C. Lee et al. provide
the essential oil and/or extracts of herb Zanthoxylum alatum
and Zingiber officinale for its antioxidant and antimicrobial
properties, respectively. O. O. Igbinosa et al. and C.-C. Lee
et al. provide the animal experiments using extractsfrom
Jatropha curcas (Linn) leaf and from supercritical carbon
dioxide extracted ginger, respectively. Three studies (F. M.
Al-Jasass and M. S. Al-Jasser, X.-W. Chen et al., and C.-Y.
Lo et al.) focus on biological functions of the compounds
fromSaudiArabia herbs, Chinese herbHuang Lian (Rhizoma
coptidis), and fromAlpinia galangal, respectively. Further, C.-
Y. Yen et al. provide the toxicological study for cardiotoxin III
in growth inhibition of oral cancer. C.-Y. Lin et al. provide a
review article for the chemoprevention of cytochrome P450
in oral potentially malignant disorders (OPMDs) patients in
terms of betel quid metabolism. S.-S. Liang et al. introduce
the novel technique for onlinemonitoring oxidative products
andmetabolites of nicotine based on tandem mass spectrometry.
S
ome papers introduce the bioinformatics methods or
resources to study or review the natural products-related
studies. L. Wang et al. introduce the gene ontology (GO)
network for the systems-theoretical analysis of human hepatocellular
carcinoma. Y.-C. Lin et al. provide the database
(TIPdb) for anticancer, antiplatelet, and antituberculosis phytochemicals
from indigenous plants in Taiwan. Three papers
(W.-H. Huang et al. and J.-Y. Tang et al.) provide the drug
discovery for cancer and disease therapy in terms of RNA
editing, alternative splicing, and long noncoding RNAs as
well as the summary for their bioinformatics resources.
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Citation
Chang, H.-W., L.-Y. Chuang, et al. (2013). "Natural Products: Bioactivity, Biochemistry, and Biological Effects in Cancer and Disease Therapy." The Scientific World Journal 2013.