Development of the clay reinforced bioceramics of gelatinsodium alginate composite scaffold for potential tissue engineering applications

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Date
2015
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UMT, Lhr
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A series of gelatin/sodium alginate/hydroxyapatite composite scaffolds has been prepared by using the phase separation method. The prepared spongy materials were freeze dried and subjected to dissolution test using the Ringer’s solution, which resulted in 70% dissolution and 30% retention of the materials. The porosity of the prepared materials were calculated through density measurement method. The porosity was found 82% with 150 µm pore size on average. Mechanical properties of the prepared scaffolds were determined using Instron 4502 mechanical tester. The properties like high porosity, good mechanical strength suggest that such sponges can be potentially utilized in bone tissue engineering.
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