(University of Management and Technology, 2017) Shumila Azam
A novel Schiff base 2-(((4H-pyrazol-4-yl)imino)methyl)-6-ethoxyphenol is synthesized by condensation reaction between Salicylaldehyde and 4-amino-1,2,4-Triazole. Further five metal complexes are prepared by the reaction between Schiff base and metallic salts. The prepared compounds are being characterized by FT-IR, 1H-NMR, Uv-Vis spectroscopy and conductance measurement. Schiff base and its metal complexes are soluble in dimethyl sulfoxide. Molar conductance values showed that they are non-electrolytes The characteristic peaks of FT-IR appeared at 1600 cm-1 for ligand which confirms the presence of azomethine group (-N=CH). While the signal appeared at 9.206 ppm on 1H-NMR spectrum of ligand is characteristic for azomethine group. Uv-Vis spectrum of ligand showed λmax at 295 nm. Schiff base and its metal complexes are evaluated for their antibacterial activity. Well diffusion method is used to observe their antibacterial activity. Results indicated that ligand and its metal complexes are good antimicrobial agents. Zinc complex showed highest activity among all the complexes.