Browsing by Author "UZMA AZAD"

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    Serum concentration of thyroid hormone in obese women in lahore pakistan - a clinical study
    (UMT, Lhr, 2018) UZMA AZAD
    We studied and compared thyroid function tests in 265 obese women and as many normal weight women at CENUM mayo hospital Lahore. All of them were female. Their mean (+ SD) age and height was comparable (P>0.05) but average weight, BMI, hip circumference, waist circumference and hip-waist ratio was significantly higher in obese women (P<0.05). Overall incidence of thyroid dysfunction was observed in 42(15.8%) obese patients and 53 (20%) control group patients. Hypothyroidism was detected in 30(11.3%) patients among obese and 19(7.2%) patients from control group. Overt hypothyroidism was observed in 19(7.2%) obese and 9(3.4%) control women. Subclinical hypothyroidism was detected in 11(4.2%) obese and 9(3.4%) control women. Hyperthyroidism was observed in 12(4.5%) patients among obese women, 2 have overt hyperthyroidism and 10 have subclinical hyperthyroidism. In control group 34(12.8%) patients had hyperthyroidism: 15 patients have overt hyperthyroidism and 19 have subclinical hyperthyroidism. Thus incidence of hypothyroidism was more in obese female than control group and incidence of hyperthyroidism was observed more in lean group as compared to obese patients. Acomparison of mean thyroid hormone parameters of euthyroid obese and control women showed that mean FT4 was significantly lower in obese euthyroid women while mean levels of FT3 and TSH were comparable.