Browsing by Author "Tahreem Saleem"

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    GC-MS studies of essential oil of peganum harmala L. And their antioxidant activity
    (University of Management and Technology Lahore, 2017) Tahreem Saleem
    Peganum harmala L. is a perennial plant belongs to family zygophyllaceae, usually known as hurmur, harmal or esfand. It is an important medicinal plant because it shows certain therapeutic and pharmacological effects. Chemical composition of Peganum harmala L. usually consists of phytochemicals, essential oil and fixed oil. The purpose of this study was to extract the essential oil from the leaves and seeds of Peganum harmala L. by hydro-distillation method using Dean-Stark apparatus and to characterize this oil by GC-MS. Total nine constituents of volatile were identified from the seeds and leaves of Peganum harmala L. Antioxidant activity was determined by DPPH radical scavenging and antibacterial activity was determined well diffusion method from the essential oil of Peganum harmala. Best antioxidant activity was revealed by the essential oil at 100 µg/mL with the percentage inhibition 98.085. Antibacterial activity was determined by essential oil against four bacterial strains but best activity was revealed against Staphylococcus aureus and Escherichia coli by well diffusion method. This showed the medicinal properties of essential oil Peganum harmala L. against bacteria and oxidative species which produced in the body.