Browsing by Author "Saroosh Zahoor"

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    Analyzing the efficacy of sofosbuvir in HCV patients infected with 3a genotype in pakistan
    (UMT, Lhr, 2017) Saroosh Zahoor
    Background: Hepatitis C is caused by hepatitis C virus and has infected 11 million people in Pakistan. 97 % of the patients are infected with 3a genotype of HCV. So, Sofosbuvir was used against HCV patients infected with 3a genotype. Methodology: This study was conducted at Mayo hospital Lahore. 217 patients of hepatitis C infected with 3a genotype were included in it. All of them were suffering from compensated chronic liver disease. 52 patients did not give follow up for given reasons: 32 patients could not be contacted to give follow up at the end of therapy and 20 patients were non-compliant. 165 patients continued the therapy with proper follow up, out of which 11 patients discontinued the therapy due to adverse events and 154 patients completed the therapy i.e 24 weeks. 150/154 patients showed positive response and 4 patients showed negative results against therapy. All patients were treated with SOF (once daily) plus RBV (trice a daily). Results: Results of this study came out to be: 150/154 (97 %) patients showed positive response against Sofosbuvir plus ribavirin out of which 59 (36 %) were male and 91 (61 %) were female. Conclusion: Sofosbuvir showed good results against HCV patients infected with 3a genotype in Pakistan.
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    Analyzing the efficacy of sofosbuvir in HCV patients infected with 3a genotype in Pakistan
    (University of Management and Technology Lahore, 2017) Saroosh Zahoor
    Hepatitis C is caused by hepatitis C virus and has infected 11 million people in Pakistan. 97 % of the patients are infected with 3a genotype of HCV. So, Sofosbuvir was used against HCV patients infected with 3a genotype. Methodology: This study was conducted at Mayo hospital Lahore. 217 patients of hepatitis C infected with 3a genotype were included in it. All of them were suffering from compensated chronic liver disease. 52 patients did not give follow up for given reasons: 32 patients could not be contacted to give follow up at the end of therapy and 20 patients were non-compliant. 165 patients continued the therapy with proper follow up, out of which 11 patients discontinued the therapy due to adverse events and 154 patients completed the therapy i.e 24 weeks. 150/154 patients showed positive response and 4 patients showed negative results against therapy. All patients were treated with SOF (once daily) plus RBV (trice a daily). Results: Results of this study came out to be: 150/154 (97 %) patients showed positive response against Sofosbuvir plus ribavirin out of which 59 (36 %) were male and 91 (61 %) were female. Conclusion: Sofosbuvir showed good results against HCV patients infected with 3a genotype in Pakistan.
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    A retrospective analysis on the cystic echinococcosis cases occurred in northeastern Punjab province, Pakistan
    (Korean J Parasitol, 2018) Aisha Khan; Sarmad Zahoor; Haroon Ahmed; Uzma Malik; Rabia Amin Butt; Muhammad Sultanul Muzam; Gunyakti Kilinc, Seyma; Noorulain Noor; Saroosh Zahoor; Muhammad Sohail Afzal; Hamza Mansur; Shumaila Irum; Simsek, Sami
    A retrospective study was performed to report the case occurrence of cystic echinococcosis (CE) in three hospitals of north-eastern region in Punjab Province, Pakistan. We reviewed retrospectively the clinical records of patients in 4 hospitals which were diagnosed with CE during 2012-2017. A total of 198 cases, 82 (41.4%) male and 116 (58.6%) females were detected as CE. The most Highest incidence was revealed in.... 21-30 years-old group (24.2%) followed by 41-50 (22.7%), 31-40 (16.2%), 11-20 (13.6%), 51-60 (8.1%), below 10 (5.5%), over 71 (5.1%) and 61-70 year-old group (4.5%). CE was detected in various organs of infected individuals. However, most of CE cases were detected in the liver (47.4%) and lung (18.6%). The present study indicated that CE is more or less prevalent in surveyed areas and one of the most important public health problems in Punjab Province, Pakistan.