Browsing by Author "Hamza, Anila"

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    Determination of antifungal potential of aloe vera gel
    (University of Management and Technolog, 2017) Hamza, Anila
    Medicinal plants play an important role in traditional treatments to cure a variety of diseases. Aloe vera (A. vera) is one of these traditional herbal medicinal plants which belongs to the family Liliaceae. It is a cactus like plant with short stem and fleshy leaves, and grow in hot and dry areas. Phytochemical compounds such as lignins, saponins, flavonoids, tannins, alkaloids, steroids and anthraquinone had been reported from the extract of A. vera. Reports show that it has antifungal, antibacterial, anti-inflammatory, antidiabetic, antiulcer and antioxidant activitities. The plant has been used for the treatment of fever, inflammation, osteoarthritis, asthma, skin diseases, wound healing, diabetes, and stomach ulcers. One of the aims of the present study was to investigate the antifungal activity of A. vera gel against some pathogens. Three extracts that is methanol, n-hexane and gel of A. vera were analyzed for the antifungal activity against Candida albicans and Saccharomyces cerevisiae. To determined antifungal activity agar well diffusion method was used. Gel of A. vera showed maximum antifungal activity against C. albicans with the zone of inhibition 27 mm at 72 hours. While extracts against S. cerevisiae with the zone of inhibition 14 mm at 72 hours showed least antifungal activity. The present study depicted that the gel of A. vera has better antifungal activity than methanol extract so it will be more useful in medical treatments. Second aim was to estimate the antioxidant potential, total phenolic content (TPC) measured by Folin-Ciocaletu reagent. The gel of A. vera showed GAE value 12819. Methanol extract showed GAE value 5223. n-hexane showed GAE value 2653. It has reported that the gel showed maximum GAE value against methanolic and n-hexane extract of A. vera