Browsing by Author "Ayesha Amin"

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    Development of English Vocabulary Test for School Children of Grade 6th, 7th and 8th
    (University of Management & Technology, 2018) Ayesha Amin
    The present study aim to develop the indigenous English vocabulary test for school children grade 6th, 7th and 8th class with the age range of 10 to 15 years of (M=13.10; SD=1.09). The study was divided into two phases the first phase consist on the development of test in which first of all the item were selected from the given glossary from books of the school children, secondly after piloting the increasing order of difficulty was calculated. The second phase was consisted of establishing the psychometrics properties of test in which test re-test reliability and concurrent validity showed that test was highly validate and reliable, than the main study N=300 result showed that there was significant positive correlation between vocabulary skills and grade of students as the score increase when the class of the students increase. N=300. However there is no gender differences were found in vocabulary skills. This research provide an indigenous vocabulary test which might be helpful after assessment for making intervention plan as well as provide support for further researches.
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    In silico interaction studies of spike protein from different SARS-COV-2 variants with its angiotensin-converting ENZYME-2 receptor with respect to geographical regions
    (UMT, Lhr, 2023) Ayesha Amin
    The emergence of SARS-CoV-2 in late 2019 resulted in the global pandemic of Coronavirus disease 2019 (COVID-19), causing significant disruptions in various aspects of society. SARSCoV-2 belongs to the beta Coronavirus family and is highly infectious, primarily spreading through respiratory droplets. Its genome consists of a single-stranded RNA encoding structural and nonstructural proteins. The spike protein plays a crucial role in viral attachment to host cells through interaction with the ACE2 receptor. Other structural proteins include the envelope, nucleocapsid, and membrane proteins. The virus also encodes 16 nonstructural proteins involved in various aspects of its life cycle, serving as potential targets for drug development. Understanding the structural and nonstructural proteins of SARS-CoV-2 is essential for comprehending its lifecycle and developing effective therapeutic strategies. This study provides an overview of the viral proteins, their functions, and the lifecycle of SARS-CoV-2, offering valuable insights for further research and the development of antiviral interventions.