Browsing by Author "ADNAN MIRAN"

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    Antimicrobial activity of drug loaded iron oxide magnetic nanoparticles
    (UMT, Lhr, 2019) ADNAN MIRAN
    The resistance of bacteria towards different antibiotics is considered a worldwide health problem. New mechanisms of resistance emerge and spread in the world day by day. Therefore, it is required to develop new techniques and mechanisms to overcome the effects of these diseases caused by different human pathogens. The use of various types of nanoparticles for medicinal purposes is ongoing for many years. In this research, the technique was used to combine the iron oxide nanoparticles (IONPs) with the antibiotic drug. Magnetite Nanoparticles is successfully synthesized by chemical schemes and assessed by UV visible Spectroscopy. The coating of function clutches on Magnetic nanoparticles is analyzed by FTIR. After stacking of drug (Gentamicin), drug-loaded magnetic nanoparticles are tried against two classes of microbes, and the result bares that drug-loaded magnetic nanoparticles are very fruitful antibacterial agents against Escherichia coli and Staphylococcus aureus. Gentamicin drug shows an increase in its efficiency when coated on the iron oxide nanoparticles. Maximum Zone of inhibition for E. Coli gives the best results as compared to S. Aureus and it is concluded that these synthesized magnetic nanoparticles can serve as an antibacterial agent.