Lumbar disc herniation (LDH) is a common spinal disorder that causes back pain, radiculopathy, and neurological deficits. Evidence suggests that gender, along with systemic comorbidities such as obesity and osteoporosis, influences the manifestation, severity, and progression of LDH. MRI is the gold standard for diagnosing and characterizing disc pathology, but the interplay between sex-specific features and comorbidities remains underexplored.