Synthesis, characterization and biological studies of transition metal complexes of (e)-4-((3,5-dichlorophenyl)amino)-4-oxobut-2-enoic acid

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dc.contributor.authorRizwan, Afshan
dc.date.accessioned2018-02-08T11:40:31Z
dc.date.available2018-02-08T11:40:31Z
dc.date.issued2017
dc.descriptionSupervised by: Dr. Khurram Shahzad Munawaren_US
dc.description.abstractLigand, its sodium salt and four new metal carboxylates have been prepared and characterized by FT-IR, conductometry and UV-Visible spectroscopy. All the prepared compounds were solid and obtained in solid state. They have sharp melting points and have good yield. FTIR spectroscopy proved that there is no involvement of carbonyl group and amine group in metal-ligand coordination. Only carboxylic group was involved in complex formation. Molar conductance revealed that all the compounds are non-electrolytic in nature due to very low conductance. A broad band in copper complex (CuL2) represents the presence of water molecules. UV-Visible spectra proven that all the compounds appeared in UV region (200-400nm) have shown π-π* and n-π* which indicated that all the compounds were aromatic in nature. Different concentrations of synthesized compounds were used to for inhibition of alkaline phosphatase which proved that all the compounds possess inhibitory action against ALP.en_US
dc.identifier.urihttps://escholar.umt.edu.pk/handle/123456789/2656
dc.language.isoenen_US
dc.publisherUniversity of Management and Technologen_US
dc.subjectConcentrations of synthesizeden_US
dc.subjectAlkaline phosphataseen_US
dc.subjectMS thesisen_US
dc.titleSynthesis, characterization and biological studies of transition metal complexes of (e)-4-((3,5-dichlorophenyl)amino)-4-oxobut-2-enoic aciden_US
dc.typeThesisen_US
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