Balqees AfzaalLaiba NaveedAbdul HakeemMahnam AliAnooshay HaniaHuda Mohammad Nadim2026-05-222026-05-222025https://escholar.umt.edu.pk/handle/123456789/19907Background: Up to this point, Fetal Echocardiographic Analysis of Myocardial Thickness, and Septal Integrity in Gestational Diabetic Patients and its Association with Family History of diabetes have not been accounted in Pakistan. We directed research to explore the insight using imaging element echocardiography modality for analysis of myocardial thickness and septal integrity in GDM patient along with their family history of diabetes. Aim: This study aims to evaluate early cardiac and septal changes caused by gestational diabetes and its association with family history of Diabetes. Methods: It was a cross sectional, prospective study conducted at the Echocardiography Department of “The Children Hospital Lahore”. A sample size of 89 participants with gestational diabetes was studied within the duration of 2 months. SPSS is used for statistical analysis. Results: In this study there were 89 pregnant females that have Gestational Diabetes 77 (86.5%) had a family history of diabetes, while 12 (13.5%) did not. When analyzed with septal thickness category 83.15% female with family history of diabetes exhibit septal hypertrophy and 3.37% were normal. A statistically significant (P = 0.007) association lies between family history of diabetes and septal thickness. EF were normal in majority of cases and it was statistically insignificant (p= 0.691). In the LVDd category, 56.18% of all patients with decreased LVDd had a family history of diabetes statistically significant (p= 0.006). Conclusion: In conclusion, investigation of 89 patients of GDM myocardial thickness and septal integrity has a statistically significant result with family history of diabetes.enThesis