HAFIZA BENITA AQDAS2025-12-012025-12-012016https://escholar.umt.edu.pk/handle/123456789/14352A novel Schiff base (E)-2-(((4-chloro-3-(trifluoromethyl)phenyl)imino)methyl)-6ethoxyphenol is synthesized by the reaction between 3-Ethoxysalicylaldehyde and substituted aniline in equimolar quantity. Chelates of Schiff base with transition metals Zn and Co are prepared in alcoholic solution with metal to ligand ratio of 1:2. The resulting compounds are characterized by FT-IR indicating that the ligand is a bidentate and the complexes are of ML2 type. The compounds are also tested for in vitro antimicrobial screening which show that complexes have moderate activity against tested microbial strains but slightly higher as compared to the Schiff base ligand.enThesis